Prevalence of and Risk Factors for Venous Thromboembolism in Patients With Lymphoma: A Meta-Analysis.

PROBLEM IDENTIFICATION: The risk of venous thromboembolism (VTE) in patients with lymphoma may be overlooked because patients often experience thrombocytopenia from the disease or chemotherapy. A meta-analysis was conducted to identify the prevalence of and risk factors for VTE in patients with lymphoma. LITERATURE SEARCH: A systematic search of Embase®, Web of Science, PubMed®, and Cochrane Library databases was conducted to identify relevant studies investigating VTE in patients with lymphoma. DATA EVALUATION: The methodologic quality of the eligible observational studies was assessed using the Newcastle-Ottawa Scale. Stata, version 12.0, was used to perform the meta-analysis. SYNTHESIS: Female sex, older age, history of VTE, a diagnosis of diffuse large B-cell lymphoma, Ann Arbor stage III-IV disease, a higher performance status score, bulky disease, central nervous system involvement, a white blood cell count greater than 11 × 109/L, a D-dimer level greater than 0.5 mg/L, central venous catheterization, and treatment with doxorubicin were significant risk factors for VTE. IMPLICATIONS FOR PRACTICE: This meta-analysis identified risk factors for VTE, which may provide a theoretical foundation for clinical staff to conduct early assessment and identification of high-risk VTE groups, allowing for timely intervention.

The protective role of social support on prenatal depression among pregnant women of advanced maternal age: a Three-Trimester follow-up study in China.

The aim of this study was to compare the depressive symptoms during pregnancy between pregnant women aged over 35 years and those aged less than 35 years and to evaluate the protective effect of social support in early pregnancy against prenatal depressive symptoms. One hundred and seventy one women aged over 35 years and 342 trimester-matched women aged less than 35 years were included from a level III hospital in Shenzhen, China. The self-report Edinburgh Postnatal Depression Scale (EPDS) and Social Support Rating Scale (SSRS) were used to evaluate prenatal depression and social support in early pregnancy. The proportions of women aged over 35 years who screened positive for prenatal depression were 22.8%, 23.4%, and 24.0% in the first, second and third trimesters, respectively. Advanced maternal age (≥35 years) was a positive predictor of prenatal depressive symptoms (ß = 0.747, P = 0,008). Social support, especially objective support (ß = -0.030, P = 0.002) and subjective support (ß = -0.028, P = 0.006) in early pregnancy, had stronger protective effects against prenatal depressive symptoms for women aged over 35 years than younger women. Our findings support that older pregnant women experience more depressive symptoms than younger pregnant women, and social support could serve as a targeted intervention to decrease prenatal depressive symptoms.Impact statementWhat is already known on this subject? Depressive symptoms, which are strongly associated with adverse psychosocial and birth outcomes, appear to be prevalent and change in nature. Social support is an important protective factor against prenatal depression.What the results of this study add? Pregnant women of advanced maternal age experienced more depressive symptoms than younger women during the prenatal period. Social support, especially objective support and subjective support, had stronger protective effects against prenatal depression for women aged over 35 years than women aged less than 35 years.What the implications of these findings are for clinical practice? Screening of prenatal depression should be strengthened, especially for women aged over 35 years, and improving subjective support could improve their emotional experience.

Evaluation and prediction of the connect index between the Belt and Road countries and China based on the DANP method.

Interconnection is the priority direction of the Belt and Road initiative, which can provide substantial assistance to win-win cooperation. This study establishes a new indicator system from the five dimensions of policy, infrastructure, trade, finance, and people-to-people, evaluates the connect index of 63 Belt and Road countries from 2013 to 2020 based on the DEMATEL-ANP method which removes the potential subjective interference and interaction between indicators, and predicts the trend of the connect index by using the grey model. The findings indicate that the five dimensions of the Belt and Road connectivity have unevenly developed, among which the policy coordination has achieved the least. Singapore, Russia, and Malaysia have the highest connect index, and we can find that the 10 countries with the highest connect index are basically from East Asia & Pacific and Europe & Central Asia, which possess large economic and geographical differences. Moreover, there are 17 "omission areas" characterized by low national income, poor infrastructure, low population density, and small land areas along the Belt and Road. Finally, the Silk Road Economic Belt is facing structural imbalances in connectivity, and the relation features "proximity but not affinity" between China and its neighboring countries. These conclusions are friendly cautions and have constructive policy implications for the Belt and Road countries to achieve high-quality interconnection.

Posttraumatic growth and postpartum depression in women after childbirth: The moderating role of postpartum negative life events.

AIM: This study aimed to investigate the implications of postpartum negative life events on postpartum depression and posttraumatic growth in women after childbirth. METHODS: A sample of 280 postpartum women at a level III hospital in China provided data on postpartum depression, negative life events, and posttraumatic growth with a cross-sectional design. RESULTS: The scores of both postpartum depression and negative life events exhibited a quadratic correlation with posttraumatic growth in women after childbirth, and negative life events significantly moderated the associations between depression and overall posttraumatic growth and its three dimensions: personal strength, spirit change, and relating to others. CONCLUSIONS: Women can experience positive psychological growth after childbirth, and this study provides new evidence of an interaction between postpartum depression and negative life events in the prediction of psychological growth, highlighting the moderating role of negative life events. This study could help direct mental health professionals to target interventions that provide more psychological support to reduce the impact of depression and negative life events, which will be conducive to improving women's psychological growth.